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Cystic Craniopharyngiomas Treated by Ommaya Reservoir Implantation About 4 Cases Including 2 Cases of Intracystic Injection of Bleomycin

Received: 23 March 2023     Accepted: 14 April 2023     Published: 10 May 2023
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Abstract

Introduction. Cystic craniopharyngiomas are the most common form of craniopharyngiomas. The treatment is still debated. The less aggressive and multidisciplinary approach is more recommended. Methods. We describe 4 cases of cystic craniopharyngiomas managed in our department by implantation of an Ommaya reservoir. The diagnosis was retained on imaging and in front of the appearance of the cyst puncture fluid. Intracystic chemotherapy with bleomycin was performed in 2 cases. Results. Patient’s age was 3, 34, 51 and 65 years. There were 2 female and 2 male patients. Clinical signs were dominated by headache (4 cases) and visual disturbances (4 cases). The Ommaya reservoir was placed with an endoscope in 2 cases. Postoperative insipid diabetes was noted in these 2 cases. A puncture of the Ommaya reservoir was performed on average every 3 weeks (2 cases) in the absence of Bleomycin. Infection was noted in these 2 cases. The evolution was favorable in 3 cases including the 2 cases of Bleomycin injection. Conclusion. Ommaya reservoir implantation was a satisfactory alternative to surgical excision of craniopharyngiomas. The use of the endoscope increased the risk of developing insipid diabetes. Close punctures of the reservoir increased the risk of infection. Intra-cystic Bleomycin stopped the punctures of the reservoir.

Published in International Journal of Neurosurgery (Volume 7, Issue 1)
DOI 10.11648/j.ijn.20230701.12
Page(s) 7-12
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Craniopharyngioma, Ommaya Reservoir, Bleomycin

References
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  • APA Style

    Denléwendé Sylvain Zabsonre, Eustache Kienou, Joseph Biogo, Louis Junior Comboigo, Wendlasida Serge Pacome Arnauld Yameogo, et al. (2023). Cystic Craniopharyngiomas Treated by Ommaya Reservoir Implantation About 4 Cases Including 2 Cases of Intracystic Injection of Bleomycin. International Journal of Neurosurgery, 7(1), 7-12. https://doi.org/10.11648/j.ijn.20230701.12

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    ACS Style

    Denléwendé Sylvain Zabsonre; Eustache Kienou; Joseph Biogo; Louis Junior Comboigo; Wendlasida Serge Pacome Arnauld Yameogo, et al. Cystic Craniopharyngiomas Treated by Ommaya Reservoir Implantation About 4 Cases Including 2 Cases of Intracystic Injection of Bleomycin. Int. J. Neurosurg. 2023, 7(1), 7-12. doi: 10.11648/j.ijn.20230701.12

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    AMA Style

    Denléwendé Sylvain Zabsonre, Eustache Kienou, Joseph Biogo, Louis Junior Comboigo, Wendlasida Serge Pacome Arnauld Yameogo, et al. Cystic Craniopharyngiomas Treated by Ommaya Reservoir Implantation About 4 Cases Including 2 Cases of Intracystic Injection of Bleomycin. Int J Neurosurg. 2023;7(1):7-12. doi: 10.11648/j.ijn.20230701.12

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  • @article{10.11648/j.ijn.20230701.12,
      author = {Denléwendé Sylvain Zabsonre and Eustache Kienou and Joseph Biogo and Louis Junior Comboigo and Wendlasida Serge Pacome Arnauld Yameogo and Henri Lankoande and Abdoulaye Thiombiano and Abdoulaye Sanou and Yacouba Haro and Inoussa Zoungrana and Abel Kabre},
      title = {Cystic Craniopharyngiomas Treated by Ommaya Reservoir Implantation About 4 Cases Including 2 Cases of Intracystic Injection of Bleomycin},
      journal = {International Journal of Neurosurgery},
      volume = {7},
      number = {1},
      pages = {7-12},
      doi = {10.11648/j.ijn.20230701.12},
      url = {https://doi.org/10.11648/j.ijn.20230701.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijn.20230701.12},
      abstract = {Introduction. Cystic craniopharyngiomas are the most common form of craniopharyngiomas. The treatment is still debated. The less aggressive and multidisciplinary approach is more recommended. Methods. We describe 4 cases of cystic craniopharyngiomas managed in our department by implantation of an Ommaya reservoir. The diagnosis was retained on imaging and in front of the appearance of the cyst puncture fluid. Intracystic chemotherapy with bleomycin was performed in 2 cases. Results. Patient’s age was 3, 34, 51 and 65 years. There were 2 female and 2 male patients. Clinical signs were dominated by headache (4 cases) and visual disturbances (4 cases). The Ommaya reservoir was placed with an endoscope in 2 cases. Postoperative insipid diabetes was noted in these 2 cases. A puncture of the Ommaya reservoir was performed on average every 3 weeks (2 cases) in the absence of Bleomycin. Infection was noted in these 2 cases. The evolution was favorable in 3 cases including the 2 cases of Bleomycin injection. Conclusion. Ommaya reservoir implantation was a satisfactory alternative to surgical excision of craniopharyngiomas. The use of the endoscope increased the risk of developing insipid diabetes. Close punctures of the reservoir increased the risk of infection. Intra-cystic Bleomycin stopped the punctures of the reservoir.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Cystic Craniopharyngiomas Treated by Ommaya Reservoir Implantation About 4 Cases Including 2 Cases of Intracystic Injection of Bleomycin
    AU  - Denléwendé Sylvain Zabsonre
    AU  - Eustache Kienou
    AU  - Joseph Biogo
    AU  - Louis Junior Comboigo
    AU  - Wendlasida Serge Pacome Arnauld Yameogo
    AU  - Henri Lankoande
    AU  - Abdoulaye Thiombiano
    AU  - Abdoulaye Sanou
    AU  - Yacouba Haro
    AU  - Inoussa Zoungrana
    AU  - Abel Kabre
    Y1  - 2023/05/10
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ijn.20230701.12
    DO  - 10.11648/j.ijn.20230701.12
    T2  - International Journal of Neurosurgery
    JF  - International Journal of Neurosurgery
    JO  - International Journal of Neurosurgery
    SP  - 7
    EP  - 12
    PB  - Science Publishing Group
    SN  - 2640-1959
    UR  - https://doi.org/10.11648/j.ijn.20230701.12
    AB  - Introduction. Cystic craniopharyngiomas are the most common form of craniopharyngiomas. The treatment is still debated. The less aggressive and multidisciplinary approach is more recommended. Methods. We describe 4 cases of cystic craniopharyngiomas managed in our department by implantation of an Ommaya reservoir. The diagnosis was retained on imaging and in front of the appearance of the cyst puncture fluid. Intracystic chemotherapy with bleomycin was performed in 2 cases. Results. Patient’s age was 3, 34, 51 and 65 years. There were 2 female and 2 male patients. Clinical signs were dominated by headache (4 cases) and visual disturbances (4 cases). The Ommaya reservoir was placed with an endoscope in 2 cases. Postoperative insipid diabetes was noted in these 2 cases. A puncture of the Ommaya reservoir was performed on average every 3 weeks (2 cases) in the absence of Bleomycin. Infection was noted in these 2 cases. The evolution was favorable in 3 cases including the 2 cases of Bleomycin injection. Conclusion. Ommaya reservoir implantation was a satisfactory alternative to surgical excision of craniopharyngiomas. The use of the endoscope increased the risk of developing insipid diabetes. Close punctures of the reservoir increased the risk of infection. Intra-cystic Bleomycin stopped the punctures of the reservoir.
    VL  - 7
    IS  - 1
    ER  - 

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Author Information
  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

  • Neurosurgery Department of Yalgado Ouedraogo Teaching Hospital, Ouagadougou, Burkina Faso

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